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Simparica Flea & Tick Chewables for Dogs 11.1-22 lbs (Caramel)

4.6/5 (267 Reviews)
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  • Information
  • Directions
  • Safety
  • Benefits
  • Simparica Flea & Tick Chewables FAQ
Information
Simparica Flea & Tick Chewables
  • Pet
    Dog
  • Treatment For
    Flea & Tick
  • Health Benefits
    External Parasite Protection
  • Product Type
    Flavored Tablet
  • Parasites Covered
    Fleas, Ticks
  • Minimum Age
    6 Months
  • Minimum Weight
    2.8 Pounds
  • Protects For
    1 Month
  • Can Be Given Without Food
    Yes
  • Safe For Pregnant Dogs
    No
  • Recommended For
    Puppies 8 weeks of age and older
  • Key Ingredients
    Sarolaner

Simparica Flea & Tick Chewables for Dogs 11.1–22 lbs (Caramel)

Simparica Chewables for dogs Caramel is a monthly treatment that protects your furry friend from the most common external parasites. Just one chew is enough to safeguard dogs against flea and tick infestations for four weeks. This flea and tick chew for dogs works quickly. It begins killing fleas three hours after administration, according to a lab study referenced in the product label.

Simparica for 11.1–22.0 lbs dogs comes as a tasty chewable that dogs find appealing, making it easy for you to administer. This oral formula is effective against as many as six different tick species, providing broad tick coverage throughout the month. As a direct result of killing vector ticks (black-legged ticks), it is indicated to prevent Lyme disease (Borrelia burgdorferi) infections.

Suitable For

Simparica for dogs Caramel is suitable for use in dogs from 6 months of age, weighing between 11.1 and 22.0 lbs.

Active Ingredient

Sarolaner 20 mg

Ingredients: Sarolaner

Directions
How to Use Simparica Flea & Tick Chewables for Dogs

  • Treatment with Simparica chewables may begin at any time of the year.
  • Simparica Chewables should be administered orally as a single dose, once every month.
  • The chew can be given by hand, in the food, or like other oral tablets. When giving it with food, watch your dog for some time to ensure the complete dose is consumed. If you suspect that a part of the dose is missed, give another dose.
  • If you miss a dose, give one dose immediately and continue with the monthly dosing schedule.
  • For your dog's year-round protection, give Simparica the entire year without interruption.

The table below displays the available Simparica Chewable dosage packs based on your dog’s weight.

Simparica Chewable Dosing Table:

Dog Weight (lbs) Pack Color Sarolaner Per Chew (mg) Chews Administered
2.8 – 5.5 Yellow 5 One
5.6 – 11.0 Purple 10 One
11.1 – 22.0 Caramel 20 One
22.1 – 44.0 Blue 40 One
44.1 – 88.0 Green 80 One
88.1 – 132.0 Brown 120 One
For dogs over 132.0 lbs, administer the appropriate combination of Simparica Chews.
Safety

For Dogs:

Do not administer to dogs under 6 months of age or less than 2.8 lbs of body weight. You should use it with caution in dogs with a history of seizures or neurologic disorders. The safety of these chews has not been evaluated in breeding, pregnant, or lactating dogs.

For Humans:

Simparica Chewable is not for use in humans or any other animal species. Keep them away from children, pets and uninformed people. In case of accidental ingestion, consult a physician immediately.

Are there Any Specific Storage Instructions for Simparica Chews?

You should store Simparica Chewables at or below 30°C (86°F) with excursions permitted up to 40°C (104°F).

Benefits

What are the Key Benefits of Simparica Chewables for Dogs?

  • Month-long protection: A single chew provides continuous protection for 30 days.
  • Hassle-free administration: Comes in a palatable chew that dogs accept without fuss.
  • Wide tick-coverage: Safeguards against 6 different species of ticks.
  • Lyme disease prevention: Indicated to prevent Lyme disease infections by killing black-legged vector ticks.
  • Rapid action: Begins killing fleas within 3 hours and ticks in 8 hours.
Simparica Flea & Tick Chewables FAQ

How soon can I start treating my dog with Simparica?

Simparica Chewables are safe for dogs from 6 months of age, weighing at least 2.8 lbs. You may begin treating your dog with Simparica at any time of the year.

How is Simparica Chewable different from other flea and tick products?

Simparica Chewable for dogs is a flea and tick treatment that kills fleas and six different types of ticks, including American dog ticks, Lone star ticks, Gulf Coast ticks, Black-legged ticks, Brown dog ticks and Asian longhorned ticks.

How does Simparica Chew work?

Simparica Chewable contains sarolaner as its active ingredient. After ingestion, the formula is absorbed into the dog's bloodstream and skin tissues. Once fleas and ticks bite the treated dog, they ingest sarolaner, which disrupts the nervous system of these parasites and kills them.

How effective is Simparica Chewable?

According to a laboratory study referenced in the product label, Simparica begins killing fleas 3 hours after initial administration. It reduces the number of active fleas by more than 95% within 8 hours after flea infestation and provides complete flea efficacy 24 hours after treatment. The lab studies also indicated that it provides more than 95% effectiveness against ticks 48 hours post-infestation.

How frequently should I give my dog Simparica?

Simparica Chewable for dogs is a monthly flea and tick treatment and should be given once every month.

How quickly does Simparica kill parasites?

Simparica Chewable for dogs is a quick-action formula. According to the studies referenced by the manufacturer, it starts killing fleas within 3 hours and ticks in 8 hours.

Which ticks does Simparica Chewable kill?

Simparica Chewable kills six different types of ticks, including American dog ticks, Gulf Coast ticks, Lone Star ticks, Black-legged ticks, Brown dog ticks and Asian longhorned ticks.

How is Simparica Chewable different from Simparica Trio?

Simparica only contains sarolaner as its active ingredient. As a result, it is effective against fleas and six types of ticks (including the ticks that may transmit Lyme disease infections). Simparica Trio contains moxidectin and pyrantel in addition to sarolaner. It protects dogs against heartworm disease, intestinal worms, fleas, and six tick species (including the ticks that may transmit Lyme disease infections).

How does Simparica Chewable protect from Lyme disease?

Simparica Chewable for dogs kills black-legged ticks (deer ticks) and thus blocks the infections that may cause Lyme disease in dogs.

What happens if I miss a dose of Simparica?

If you miss giving a dose, give one Simparica chewable right away and continue with a monthly dosing schedule.

Simparica Flea & Tick Chewables Reviews

4.6
Average Rating 4.6 Based on 267 Reviews
  • 5 star
     157
  • 4 star
     108
  • 3 star
     1
  • 2 star
     0
  • 1 star
     1
58%
Recommend
58% of Reviewers Recommend This Product
Write A Review
4.6/5
Average Rating 4.6
Based on 267 Reviews
Easy Flea Control Aug 22, 2026
Convenient chew that fits smoothly into our routine.
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Convenient Flea Control Aug 15, 2026
Easy chew that fits perfectly into our routine.
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Fast-Acting Relief Aug 08, 2026
Works quickly and keeps ticks away consistently. Very impressed.
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Quick and Effective Results Aug 01, 2026
Very effective and fast-acting. My dog stopped itching within a day.
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Rapid Results Jul 25, 2026
Fleas disappeared within a day.
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Fast Acting Jul 18, 2026
Starts working quickly on fleas.
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Fast Results Jul 11, 2026
Works quickly against ticks and fleas.
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Fast Results Jul 04, 2026
Works quickly against fleas and ticks.
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Fast Action Jun 27, 2026
Starts working quickly against ticks.
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Fast Results Jun 20, 2026
Acts quickly on fleas and ticks.
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Fast Action Jun 13, 2026
Starts working quickly against fleas.
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Fast Acting Jun 06, 2026
Starts working quickly on fleas and ticks.
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