TOLL FREE 1-800-214-4505 9 am to 6 pm CST (Mon-Sat)
You have no products in your cart

Register Creating an account is easy! You'll be able to checkout faster, manage auto order, track order status and more!

Frontline Plus for Dogs

In Stock
4.8/5 (124 Reviews)
Save 5% on your Auto Delivery Order! Auto Delivery & Save 5%
Select Pack
3 Doses $22.30
6 Doses $40.72
12 Doses $77.56
Select Auto Delivery Frequency
  • Information
  • Directions
  • Safety
  • Benefits
  • Frontline Plus FAQ
Frontline Plus
  • Pet
  • Treatment For
    Flea & Tick
  • Health Benefits
    External Parasite Protection
  • Product Type
  • Parasites Covered
    Adult fleas, Ticks, Flea eggs, Larvae, Pupae, Chewing lice
  • Minimum Age
    8 Weeks
  • Minimum Weight
    5 Pounds
  • Protects For
    One month
  • Safe For Pregnant Dogs
  • Recommended For
    8 weeks and older puppies
  • Key Ingredients
    Fipronil, s-Methoprene

Frontline Plus for Dogs – Fast-Acting Flea & Tick Treatment

Manufactured by Boehringer Ingelheim, Frontline Plus is the No.1 vet-recommended flea and tick treatment for canines. This easy-to-apply topical treatment combats fleas and ticks for a whole month. This topical treatment combats fleas and ticks for a whole month. It also prevents Lyme disease in dogs by killing certain species of ticks that transmit it. Due to its larvicidal properties, it stops the development of juvenile flea stages and kills them. The elimination of adult fleas, ticks, flea eggs, larvae, pupae, mites, and chewing lice is efficiently handled by Frontline Plus. Therefore, this preventive does not allow the re-infestation of parasites on your dog’s body.

Frontline Plus is waterproof after 24 hours, so you don’t have to worry about the solution being washed off when your pooch is wet. Moreover, this mighty pest killer is clinically tested to be used on breeding and lactating dogs, irrespective of their breed. Frontline Plus for Dogs is suitable to be used on adult dogs and puppies older than 8 weeks of age and weighing at least 5 lbs.

How Frontline Plus works?

Frontline Plus is formulated with two strong killing ingredients, Fipronil and (s)-Methoprene. Fipronil works as an adulticide and destroys adult fleas and ticks. While the other element, (s)-methoprene functions as a larvicide, killing the early flea stages including eggs, larvae, and pupae. These key ingredients collectively destroy all the parasites and break the flea life cycle. This long-lasting treatment kills almost 100% of adult fleas within 12 hours and eradicates ticks within 48 hours of application.

Frontline Spray

Frontline Spray is a uniquely formulated flea and tick treatment for dogs, cats, puppies and kittens. This spray formula is highly effective in eliminating flea infestations and helps in curing Flea Allergy Dermatitis (FAD) in cats and dogs. Moreover, the product provides flea protection for full 3 months and from ticks (including paralysis ticks) for 3 weeks. The product is also quite easy to administer in cats and dogs. More info on Frontline Spray.

How to Use Frontline Plus for Dogs

  • Frontline Plus is available in different packs, color coded on the basis of the dog’s weight range.
  • Weigh your pooch before selecting a pack.
  • Once the pack is in your hand, remove the applicator tube from the pack.
  • Use scissors or peel away the foil backing.
  • Hold the applicator upright and snap the tip.
  • Part your pet’s hair between the shoulder blades, until you can feel his skin.
  • Apply the entire content of the tube on that spot.
  • If you have a large breed, apply the solution at 3-4 spots.
  • Let the application site dry and keep your pet under surveillance until the spot dries.
  • Make sure you select an appropriate pack of Frontline Plus.
  • Maintain the dates of the doses. Do not overdose.
  • Wash your hands before and after treating your pet.
  • Do not use Frontline Plus on puppies under 8 weeks of age.
  • Avoid bathing the treated pet before 48 hours of application.
  • The application area should be dry, clean and unharmed when you apply the solution.
  • Don’t let your pooch lick the treated spot.
  • Store the pack at room temperature.
  • Keep the box away from pets and children.
  • In case of side effects like hyper-itching or other sensitivities, contact your vet immediately.


  • Do not treat an injured or sick canine without your vet’s consultation.
  • In case of swallowing or licking of the solution, contact poison control centre immediately.

Frontline Plus: Key Takeaways

  • Frontline Plus is the no.1 preference of the vets
  • It has been a trusted brand among pet owners for many years
  • Kills adult fleas within 12 hours of application
  • Destroys all types of ticks in 48 hours of treatment
  • Eradicates the juvenile stages of fleas 
  • Breaks the flea life-cycle and prevents its re-infestation
  • Stays effective for 30 days
  • Is water-resistant
  • Aids in treating Flea Allergy Dermatitis
Frontline Plus FAQ

How often should I apply Frontline Plus on my dog?

One dose of Frontline Plus should be applied regularly each month, year-round, for continuous protection against fleas and ticks.

How does Frontline Plus for Dogs work?

Frontline Plus is formulated with two strong ingredients: Fipronil and (s) – Methoprene. When applied to the dog’s skin, the solution spreads from the single point of application to the entire skin surface and into the sebaceous glands. These act as a reservoir, continuously replenishing the solution to the skin and coat, so it keeps working even if the dog comes into contact with water. Frontline Plus should be applied regularly each month year-round for continuous protection against fleas and ticks

Is Frontline Plus safe for puppies?

Frontline Plus is suitable for all dogs and puppies older than 8 weeks of age and weighing at least 5 lbs.

Can my dog get wet after applying Frontline Plus?

Your dog needs to remain dry for 24 hours after the application of Frontline Plus.

Is Frontline Plus safe for all dog breeds?

Yes, Frontline Plus is safe for all dog breeds.

Why is it important to use the correct pack size of Frontline Plus for my dog?

Each Frontline Plus pack size contains a different concentration of active ingredients based on the dog's weight. In order to ensure that your dog receives the optimum dose for which the product has been shown to be effective, it is essential to use the correct pack size.

Does my dog need flea and tick protection even in colder months?

Yes. Even though the chance of your dog having fleas lowers in the winter due to the milder temperatures in some regions as well as inside your house, fleas survive for much longer. Moreover, most tick species are also prevalent throughout the year.

Does my dog need flea and tick protection even if it doesn’t go outside much?

Indoor dogs can pick up fleas and ticks easily while going out for walks or even from your backyard. And, if an untreated animal or a friend visits your house, they may also bring in fleas on clothes or shoes, and your dog may get infested. Therefore, flea and tick prevention is essential even for dogs that don’t go out much.

Do I need to use other flea and tick treatments while using Frontline Plus?

No, Frontline Plus is a full-proof flea and tick treatment. It is the #1 name in flea and tick protection, and it remains effective for an entire month. If used regularly every month, there is no need to use any other treatments with Frontline Plus.

Frontline Plus Reviews

Average Rating 4.8 Based on 124 Reviews
  • 5 star
  • 4 star
  • 3 star
  • 2 star
  • 1 star
81% of Reviewers Recommend This Product
Write A Review
Great prices Sep 19, 2023
I was impressed with the selection and prices which is why I purchased from BudgetPetWorld. I received my order within two weeks. I will definitely order from them again!
Was this review helpful? 0 0
Easy application Sep 14, 2023
The tube packing makes applying easy. A good treatment for pesky parasites
Was this review helpful? 0 0
Tick destroyer Sep 02, 2023
It kills all ticks within hours. I am no more worried about these peasky parasites
Was this review helpful? 0 0
Trustworthy Aug 22, 2023
I came to know about Bravecto from my vet. It works really efficiently
Was this review helpful? 0 0
Kills all fleas Aug 08, 2023
It treats flea infestation of any level, kills and protects against all the flea infestatons
Was this review helpful? 0 0
Kills fleas & ticks wtihin hours Aug 01, 2023
Starts acting fast and kills the fleas and ticks within hours of application
Was this review helpful? 0 0
Monthly protection Jul 25, 2023
This very effective solution actually gives protection againsst parasites for whole month. I apply it regulary on my pup
Was this review helpful? 1 0
Trusted Jul 18, 2023
A trusted name for long, Frontline plus is a regular in my pet's essentials list
Was this review helpful? 0 0
Quick results Jul 12, 2023
Gives relief from fleas and ticks within hours. A sure shot repurchase for me
Was this review helpful? 0 0
Great Relief! Jul 04, 2023
The itching and irritation of my pet is gone. It is a relief to see her happy.
Was this review helpful? 0 0