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Revolution Medium Dogs 20.1-40lbs (Red)

4.8/5 (264 Reviews)
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  • Information
  • Directions
  • Safety
  • Benefits
  • Revolution FAQ
Information
Revolution
  • Pet
    Dog
  • Treatment For
    Flea, Heartworm
  • Health Benefits
    External & Internal Parasite Protection
  • Product Type
    Topical (liquid)
  • Parasites Covered
    fleas, Ticks, Heartworms, Ear Mites
  • Protects For
    One month
  • Recommended For
    6 weeks and older puppies
  • Key Ingredients
    Selamectin

Revolution Medium Dogs 20.1 - 40 lbs (Red)

Revolution Red for Dogs is a broad-spectrum treatment, designed to protect your furry friends from both internal and external parasites. One monthly application safeguards against fleas, ticks, heartworm disease, sarcoptic mange and ear mites. This topical treatment has been trusted by veterinarians to help protect dogs for over 25 years.

Revolution for Medium Dogs 20.1-40 lbs is suitable for dogs from 6 weeks of age, making it safe for young puppies. According to Zoetis USA, it has been tested safe in more than 100 different pure and mixed breeds of healthy dogs. When used as indicated, Revolution heartworm prevention for dogs works with systemic action and prevents the development of adult heartworms. It is effective at critical life stages of fleas and controls tick infestations, providing the comprehensive coverage your dog needs.

Suitable For

Revolution Red for Dogs is suitable for dogs from 6 weeks of age, weighing between 20.1-40 lbs.

Active Ingredient

Selamectin 120 mg

Ingredients: Selamectin

Directions
How to Use Revolution for Dogs

  • Weigh your dog and select the dosage pack closest to your dog's weight.
  • Take an applicator out of the package.
  • Firmly press the cap of the applicator to puncture the seal. A clicking sound confirms that the seal is successfully broken.
  • Remove the cap and check whether the applicator is open.
  • Part your dog's hair between the shoulder blades at the base of the neck until the skin is visible.
  • Squeeze the applicator multiple times in one spot after placing it on the dog's skin and empty the entire contents.
  • Keep the applicator squeezed and lift it away from the application site to remove.
  • Do not massage the liquid into the dog's skin after applying.
  • To protect your dogs from heartworm disease, apply one dose every month throughout the year. This treatment may be applied at least within one month after the first exposure of your dog to mosquitoes and monthly afterwards until the end of the mosquito season. Apply the last dose within one month after the last exposure to mosquitoes.

The table below shows the available dosage packs of Revolution for Dogs based on the dog's weight.

Revolution for Dogs Dosing Table:

Dog Size Dog Weight Pack Color Tube Volume Selamectin (mg/tube) Doses Administered
Puppies Up to 5 lbs Pink 0.25 ml 15 mg One
Very Small Dogs 5.1 – 10.0 lbs Purple 0.25 ml 30 mg One
Small Dogs 10.1 – 20.0 lbs Brown 0.50 ml 60 mg One
Medium Dogs 20.1 – 40.0 lbs Red 1.00 ml 120 mg One
Large Dogs 40.1 – 85.0 lbs Green 2.00 ml 240 mg One
For dogs over 85.0 lbs, administer an appropriate combination of Revolution.
Safety

For Dogs:

Revolution for dogs is not indicated for puppies under 6 weeks of age. Do not use it on sick, debilitated or underweight dogs. It can be used in pregnant, breeding and lactating dogs. This treatment has been tested to be safe for pure and mixed breeds of healthy dogs, such as avermectin-sensitive collies and heartworm-positive dogs.

Test your dogs for existing heartworm infections before using it. Treat dogs infected with adult heartworms at the discretion of the veterinarian. Clinical studies referenced in the label indicate that it can be used with vaccines, antiparasitics, anthelmintics, antibiotics, steroids, collars, shampoos and dips.

For Humans:

This topical treatment is not indicated for use in humans. Keep it away from children and uninformed people. Do not allow children or anyone to come in contact with the treated dog until four hours after the application. People with known hypersensitivity to selamectin should consult their healthcare professional before handling this treatment.

General:

You should keep this product away from heat, sparks, open flames or other sources of ignition.

Are there Any Specific Storage Instructions for Revolution for Dogs?

Store it below 30°C (86°F).

Benefits

What are the Key Benefits of Revolution for Dogs?

  • Vet-recommended: Trusted by veterinarians for over 25 years.
  • Broad-spectrum coverage: Protects from fleas, ticks, heartworm disease, ear mites and sarcoptic mange.
  • Breaks flea cycle: Kills adult fleas and prevents flea eggs from hatching, preventing subsequent infestations.
  • Easy dosing: Once monthly topical treatment allows simple and convenient dosing.
  • Safe for puppies: Indicated for use in puppies from 6 weeks with no minimum weight.
Revolution FAQ

What does Revolution do for my dog?

When applied as indicated, Revolution for dogs protects puppies and dogs from fleas, ticks, heartworm disease, ear mites and sarcoptic mange.

How does Revolution for dogs work?

Revolution for dogs contains the active ingredient selamectin. Once applied, this topical formula is absorbed into the bloodstream through the skin and then distributed to the rest of the body. The concentrations of the active ingredient, selamectin, in the dog's tissues and blood prevent heartworm disease by inhibiting the growth of microfilariae. The active formula on the dog's skin helps protect from other external parasites.

How effective is Revolution for dogs?

Revolution topical for dogs kills more than 95% of fleas on dogs within 36 hours, according to a lab study referenced by Zoetis. The active ingredient, selamectin, prevents the development of adult heartworms when administered within one month of exposure.

Can I use Revolution on dogs with seizures?

Before administering Revolution to your dog with a history of seizures, you should consult a veterinarian.

Can I bathe my dog after applying Revolution?

Before bathing your dog, you should allow the application to completely absorb into the dog's skin and let the application site dry. After applying the treatment, you should wait about 24 hours before you bathe your pet.

How can I replace my dog's previous heartworm protection with Revolution?

When switching heartworm preventives, you should administer the first dose of Revolution within one month of the last dose of their former treatment.

Is Revolution for dogs effective against ticks?

Revolution for dogs controls tick infestations caused by American dog ticks.

Can I use Revolution with other treatments?

According to clinical studies referenced in the product label, Revolution for dogs can be used with antiparasitics, anthelmintics, antibiotics, vaccines, steroids, collars, shampoos and dips.

What happens if I forget to dose my dog with Revolution?

If you miss a dose, administer one dose immediately and resume with the monthly schedule.

Revolution Reviews

4.8
Average Rating 4.8 Based on 264 Reviews
  • 5 star
     207
  • 4 star
     56
  • 3 star
     1
  • 2 star
     0
  • 1 star
     0
78%
Recommend
78% of Reviewers Recommend This Product
Write A Review
4.8/5
Average Rating 4.8
Based on 264 Reviews
Quick Monthly Care Aug 20, 2026
Easy application that fits neatly into our routine.
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Simple Monthly Care Aug 13, 2026
Quick to apply and easy to incorporate into pet care.
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Simple Monthly Care Aug 06, 2026
Easy to use and keeps my pet consistently protected.
Was this review helpful? 0 1
Simple and Reliable Care Jul 30, 2026
Simple monthly routine and highly effective. My pets have stayed parasite-free.
Was this review helpful? 0 1
Simple Care Jul 23, 2026
Easy application with great results.
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Simple Routine Jul 16, 2026
Easy monthly application.
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Easy Monthly Care Jul 09, 2026
Simple to apply and works well.
Was this review helpful? 1 0
Monthly Ease Jul 02, 2026
Simple application and great results.
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Monthly Care Jun 25, 2026
Keeps parasites in check.
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Easy Routine Jun 18, 2026
Simple monthly application with good results.
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Easy Routine Jun 11, 2026
Simple monthly application that works.
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