icon
TOLL FREE 1-800-214-4505 Mon-Fri 7 AM - 7 PM PST / Sat 7 AM - 4 PM PST
icon
You have no products in your cart
icon
OR

Register Creating an account is easy! You'll be able to checkout faster, manage auto order, track order status and more!

Credelio Plus for Dogs

4.6/5 (71 Reviews)
Select Pet's Weight :
Select Pack:
Frequency:
  • Information
  • Directions
  • Safety
  • Benefits
  • Credelio Plus FAQ
Information
Credelio Plus
  • Pet
    Dog
  • Treatment For
    Flea, Tick and Worm
  • Health Benefits
    Gastrointestinal Nematodes, Heartworm, Infestation of Fleas and Ticks
  • Product Type
    Chewable Tablet
  • Parasites Covered
    Fleas, Heartworm, Roundworm, Hookworm, Whipworm
  • Protects For
    One Month
  • Recommended For
    Dogs and Puppies 8 weeks and Older
  • Key Ingredients
    Milbemycin Oxime

What is Credelio Plus for Dogs?

Credelio Plus for Dogs is a broad-spectrum treatment designed to protect your canine friends from both internal and external parasites. A single dose provides protection from fleas, ticks, heartworm disease, intestinal worms and mites. This all-in-one dog parasite treatment comes in a small, tasty beef-flavored chew that dogs love, making administration easy even for fussy dogs.

Credelio Plus monthly flea and worm treatment features a unique combination of two ingredients: extra-purified lotilaner and milbemycin oxime for comprehensive protection. The treatment is suitable for use in various dog breeds from 8 weeks of age. These flea and tick chews are available in five dosage strengths to suit dogs of various sizes.

Suitable For

Credelio Plus for dogs is suitable for use in puppies and dogs from 8 weeks of age, weighing 3.0 lbs or greater.

Credelio Plus Indications

  • Kills fleas before they can lay eggs.
  • Helps control flea allergy dermatitis (FAD) by controlling adult fleas.
  • Helps reduce the risk of flea tapeworms by controlling fleas.
  • Treats & controls tick infestations of Brown Dog ticks & Asian longhorned ticks.
  • Prevents heartworm disease caused by Dirofilaria immitis.
  • Treats & controls roundworms, hookworms & whipworms.
  • May be used in the control of certain mite infestations.

Ingredients: Lotilaner, Milbemycin oxime

Directions
How to Use Credelio Plus for Dogs

  • Weigh your dog and select the pack that closely matches your dog's weight.
  • You may begin your dog's treatment with Credelio Plus at any time of the year.
  • Credelio Plus should be administered once every month, preferably on the same date each month.
  • The chew can be given directly into the dog’s mouth as other tablets or pills.
  • It can be given with food or within 30 minutes of feeding your dog. Watch your dog closely after dosing and ensure that it consumes the entire dose. If a part of the dose is missed, give another full dose.
  • For heartworm prevention, start one month before mosquitoes become active and continue monthly through the end of the mosquito season.
  • When switching to Credelio Plus from another heartworm preventive, administer the first dose of this chew within one month of the last dose of the previous preventive.
  • If you miss a dose, give one dose immediately with food and resume with the monthly dosing schedule.

The table below displays the available packs of Credelio Plus based on the dog’s weight.

Credelio Plus for Dogs Dosing Table:

Dog Size Dog Weight Pack Color Lotilaner Per Chew Milbemycin oxime Per Chew Chews Per Month
Extra Small Dogs 3.0 – 6.0 lbs Orange 56.25 mg 2.11 mg One
Small Dogs 6.0 – 12.0 lbs Yellow 112.50 mg 4.22 mg One
Medium Dogs 12.0 – 24.0 lbs Green 225.0 mg 8.44 mg One
Large Dogs 24.0 – 48.0 lbs Purple 450.0 mg 16.88 mg One
Extra Large Dogs 48.0 – 100.0 lbs Red 900.0 mg 33.75 mg One
For dogs over 100.0 lbs, administer the appropriate combination of Credelio Plus Chews.
Safety

For Dogs:

Before beginning the treatment with Credelio Plus, dogs should be tested for existing heartworms. Infected dogs should be treated to remove adult heartworms as per the vet's recommendations. This treatment should not be given to pregnant or lactating dogs. The safety of these chews has not been evaluated in pregnant or lactating dogs, heartworm-positive, breeding male and female dogs. Consult your veterinarian before use.

This flea and worm treatment is not indicated for use in puppies under 8 weeks of age or below 3 lbs of body weight.

For Humans:

Credelio Plus is not indicated for use in humans or any other animal species. You should keep these chews out of the reach of children and uninformed people. Avoid contact with your eyes and wash your hands after handling the treatment.

Are there Any Specific Storage Instructions for Credelio Plus?

Credelio Plus chews should be stored below 30°C at room temperature.

Benefits

What are the Key Benefits of Credelio Plus for Dogs?

  • Broad-spectrum protection: Safeguards against a range of external and internal parasites, including ticks, fleas, heartworm disease, gastrointestinal worms and mites for one month.
  • Quick & persistent action: Offers immediate treatment & persistent flea killing activity for one month.
  • Palatable chew: Small, beef-flavored chews make administration simple and hassle-free.
  • Unique formula: Combines extra-purified lotilaner and milbemycin oxime for all-round protection.
  • Suitable for young dogs: Indicated for puppies and dogs from 8 weeks of age.
Credelio Plus FAQ

Is Credelio Plus safe for my puppy?

Credelio Plus is indicated for puppies and dogs as young as 8 weeks that weigh at least 3 lbs.

What parasites does Credelio Plus protect my dog against?

Credelio Plus dog treatment protects dogs against fleas, ticks, heartworm disease, roundworms, hookworms, whipworms and mites.

How frequently should I administer this treatment to my dog?

You should administer one dose of Credelio Plus every month, preferably on the same date each month.

How does Credelio Plus for dogs work?

Credelio Plus contains lotilaner and milbemycin oxime. This combination works systemically and provides comprehensive protection to dogs. The formula interrupts the transmission of nerve signals in parasites. This causes uncontrolled neuromuscular activity and death of the parasites. Lotilaner targets external parasites, such as fleas and ticks, whereas milbemycin oxime prevents heartworm infections and protects from intestinal worm infections.

What happens if I miss a dose of Credelio Plus?

If you miss a dose, immediately give a dose with food and continue with monthly dosing. Check your dog for ticks and remove them if you find any.

My dog spits up the chew or refuses to take this chew. What should I do?

When your dog refuses or spits up the chew, you may give the chew with their favorite treat and encourage them to take the chew.

Should I give this treatment to my dog with food?

Yes, Credelio Plus should be administered with your dog's food or within 30 minutes of feeding your dog.

Is Credelio Plus effective against existing flea infestation on my dog?

Yes, Credelio Plus is effective against existing fleas on your dog. It also helps reduce the risk of reinfestation by fleas for one month.

Why do I still see fleas on my dog after giving Credelio Plus?

Credelio Plus kills adult fleas after they take the blood meal from the treated dog. The treatment begins killing adult fleas within hours of administration. However, the majority of the flea population is in the form of immature life stages of fleas, such as eggs, larvae and pupae, which take longer to be eliminated from your home. Therefore, environmental flea control is essential.

What intestinal worms does Credelio Plus protect my dog against?

Credelio Plus protects dogs from roundworms, hookworms and whipworms. It also helps reduce the risk of flea tapeworms by controlling fleas.

Can I use Credelio Plus with my dog's other treatments?

According to the manufacturer, Credelio Plus has been used safely with various dog treatments. For the safety of your dog, talk to your veterinarian before using it with other treatments.

Credelio Plus Reviews

4.6
Average Rating 4.6 Based on 71 Reviews
  • 5 star
     44
  • 4 star
     27
  • 3 star
     0
  • 2 star
     0
  • 1 star
     0
61%
Recommend
61% of Reviewers Recommend This Product
Write A Review
4.6/5
Average Rating 4.6
Based on 71 Reviews
Convenient Chewable Care Aug 18, 2026
Easy-to-give chew that simplifies parasite prevention.
Was this review helpful? 0 0
Smooth Treatment Option Aug 04, 2026
Easy to give and works efficiently without side effects.
Was this review helpful? 0 1
Smooth and Effective Treatment Jul 28, 2026
Effective and easy to give. My dog had no side effects at all.
Was this review helpful? 0 1
Easy Dose Jul 21, 2026
Simple chew with good coverage.
Was this review helpful? 0 1
Easy Chew Jul 14, 2026
Simple monthly routine.
Was this review helpful? 0 1
Convenient Chew Jun 30, 2026
Easy monthly routine and effective.
Was this review helpful? 0 1
Easy Chew Jun 23, 2026
Simple and effective monthly chew.
Was this review helpful? 1 0
Dual Protection Jun 16, 2026
Covers fleas and worms efficiently.
Was this review helpful? 0 0
Dual Action Jun 09, 2026
Protects against fleas and worms.
Was this review helpful? 0 0
Dual Action Jun 02, 2026
Covers fleas and worms together.
Was this review helpful? 0 0
X

Site Preferences

Your Shipping Destination
Display Currency
*Payments are processed in USD.
icon