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Advantage Multi (Advocate) For Dogs

4.8/5 (82 Reviews)
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Advantage Multi (Advocate)
  • Pet
  • Treatment For
    Flea, Worm, Heartworm
  • Health Benefits
    External Parasite Protection, Internal Parasite Protection
  • Product Type
    Topical, Spot-on
  • Parasites Covered
    Flea, Heartworm, Hookworm, Roundworm, Whipworm, Sarcoptic Mange, Ear Mite
  • Protects For
    1 Month
  • Recommended For
    Puppies 7 weeks of age and older
  • Key Ingredients
    Imidacloprid, Moxidectin

Why Choose Advantage Multi?

5-in-1 Protection
A single dose provides protection against five different parasites including fleas, heartworms, intestinal worms (roundworms, hookworms & whipworms), and sarcoptic mange.

Safe For Puppies & Adult Dogs
Recommended for use in 7 weeks and older puppies and dogs that weigh 3lbs or more

Easy-to-apply Topical Treatment
No gulping. Ideal for dogs that struggle with oral treatments

Once-a-month Application
Monthly application eliminates worms and keeps dogs protected for 30 days.

Heartworm protection for non-stop 30 days

Heartworm disease can be fatal for your dog, if not provided with an effective preventive treatment. The active component of Advantage Multi (moxidectin), is quick to get absorbed in dog's skin, killing the parasites for all month long. Advantage Multi (Advocate) gives you a second chance if you fail to remember dosing. Just give a dose as soon as you recall dosing and continue with monthly regimen.

A single dose is enough for five parasites

Advantage Multi for dogs kills adult fleas and prevents flea infestations. It kills parasites through contact, so your dog does not have to take a bite from the insect. Advantage Multi effectively prevents heartworm disease; treats and controls various intestinal worms such as roundworms, hookworms, and whipworms. Plus, it treats and controls sarcoptic mange infection.

How Advanatge Multi works?

Advantage Multi (Advocate) is composed using two key ingredients, Imidacloprid and Moxidectin. These ingredients destroy internal and external parasites by targeting their neural transmission. They dismantle the invertebrate nerve and muscle cells by attacking the central nervous system. These actions cause paralysis and eventually kill the pests. Almost 98-100% fleas are killed within 12 hours of this treatment’s application.

Manufacturer: Bayer

How to Use Advantage Multi (Advocate)

  • Get your canine tested for heartworm infestation before starting with this spot-on.
  • Treat him with Advantage Multi only if he is not infected with heartworms.
  • Check the pet’s weight and select a pack with weight range in which your canine’s weight falls.
  • Make the dog stand in a comfortable position.
  • Part fur between the shoulder blades until his skin is visible.
  • Break off the pipette’s seal.
  • Place the tip of on open pipette on the bare area.
  • Pour the entire content on the application site.
  • Allow the treated area to dry.
  • For large dogs, pour the content at 3-4 spots starting from the base of the skull to the base of the tail.
  • Advantage Multi for dogs should be applied topically once every month
  • The recommended minimum dose is 4.5mg/lb (10mg/kg) for imidacloprid and 1.1mg/lb (2.5mg/kg) for moxidectin.

Advantage Multi Dosage:

Dog Weight(Lbs)

Dog Weight(Kg)

Tube Size(mL)

Imidacloprid (mg)

Moxidectin (mg)

3 - 9

1.4 – 4.1




9.1 – 20

4.1 – 9.1




20.1 – 55

9.1 – 25.0




55.1 – 88

25.0 – 40.0




For over 88lbs dogs, use appropriate combination of Advantage Multi doses.

  • Dogs aging less than 7 weeks are not to be treated with Advantage Multi.
  • Do not treat canines allergic to the contents of this spot-on.
  • Treat your pet in an isolated space.
  • Keep the pack away from children and pets.
  • Do not smoke, drink or chew gum while treating your pet.
  • Clean your hands before and after application.
  • Don’t let your pet lick the application site.
  • Bathe your pet only after 48 hours of treatment.
  • Follow the dosage instructions mentioned in the manual.


  • Do not treat pregnant, sick, weak, lactating and breeding pets without consulting your vet.

Warning:Dogs of some breeds like collies including border collies are sensitive to moxidectin. They can suffer more or less serious adverse effects if treated at dose rates slightly higher than the recommended ones. Consequently, dosing must be as accurate as possible.

What is Advantage Multi(Advocate)?

Advantage Multi, also known as Advocate is one of the most sought after treatments from the house of Bayer. Advantage Multi kills and controls fleas, heartworms, gastrointestinal worms (hookworm, roundworm and whipworm), sarcoptic mange, demodicosis, and ear mite infestation in canines. This topical solution is easy to apply and tested safe for adult canines and puppies older than 7 weeks of age. This powerful parasitic preventive works against internal and external pests for an entire month. Using Advantage multi ensures safety from the unhealthy infestations irrespective of the dog’s breed.

Advantage Multi: Key Takeaways

  • Easy and hassle free application
  • Kills 100% fleas within 12 hours of application
  • Prevents heartworm infestation in dogs
  • Destroys and controls the growth of gastrointestinal worms excluding tapeworms
  • Works efficiently against lice, ear mites, demodex mites and sarcoptic mange
  • Quick mode of action
  • Remains effective for 30 days
  • Cost effective, all in one spot-on
  • Freedom from remembering different dates for flea treatment, worming and heartworm dose

What is the ideal age for my puppy to use Advantage Multi?

Advantage Multi for dogs is recommended for use in puppies from as young as 7 weeks of age, weighing 3lbs or more.

How does Advantage Multi work?

Advantage Multi For Dogs is made of two active ingredients; imidacloprid and moxidectin. Once applied, imidacloprid quickly gets spread across dog's skin and coat. It kills fleas as soon as they come in contact with the animal's skin. Moxidectin gets absorbed through dog's skin into subcutaneous fat and the bloodstream. It prevents heartworms, treats and controls gastrointestinal worms, and treats sarcoptic mange infections.

How often should I use Advantage Multi on my dog?

Advantage Multi should be used all year-round, once every month for protection against fleas, heartworms, and intestinal worms throughout the year.

Which Advantage Multi dose should I use if my dog weighs more than 88lbs?

If your dog weighs more than 88lbs, use an appropriate combination of Advantage Multi doses. Consult a vet if required.

Can I bathe my dog after applying Advantage Multi?

It is recommended bathing the dog prior to the treatment. Apply the dose once dog's skin is completely dry. Avoid shampooing as often as once a week as it can diminish product efficiency against fleas. Use a soap-free pet shampoo instead.
Avoid shampooing your pet as often as once a week as it can diminish product efficiency against fleas. Use a soap-free pet shampoo instead. Shampooing 90 minutes after application does not lower the effectiveness against heartworms. Water immersion or shampooing four days after product usage does not hamper its efficiency against fleas.

What happens if I miss a dose of Advantage Multi?

Advantage Multi For Dogs is a monthly treatment. If you miss a dose, apply one immediately as soon as you recollect dosing and continue with monthly dosing schedule.

What are the packaging specifications of Advantage Multi for dogs?

Advantage Multi for dogs is available in 3 doses, 6 doses, and 12 doses pack size.

Advantage Multi (Advocate) Reviews

Average Rating 4.8 Based on 82 Reviews
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Awesome May 15, 2023
An all-in-one protection.
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Always use it Apr 11, 2023
Always use this for my pet.
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Advantage Multi Apr 01, 2023
5 star
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Love it Mar 07, 2023
Love using this on my pet, effective results and no side effects,
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Best choice! Jan 27, 2023
This is the best to have for my pet, no more issues with the parasites!
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Amazing results Dec 13, 2022
I've always had amazing results while using this, never been disappointed.
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Easy to use Nov 07, 2022
It is very easy to use, effective, and lasts for a long time.
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Efficient Sep 28, 2022
An efficient and fast working treatment against parasites.
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Amazing Aug 30, 2022
Saved a stray recently and started using this as per the vet recommended. Coco is a part of the family now.
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