Simparica TRIO for Dogs

• Simparica Trio should be administered orally, as a single dose, once every month.
• You can administer the chew with or without food. When giving it with food, watch your dog to ensure the complete dose is consumed.
• When you forget a dose, give one dose immediately and continue with the monthly schedule.
• You can begin your dog's treatment with Simparica Trio at any time of the year when using it for flea, tick and flea tapeworm protection.
• For heartworm prevention, give Simparica Trio year-round. The chew should be given at least within one month after the dog's first exposure to mosquitoes and continuing until at least one month after the dog's last seasonal exposure.
• For uninterrupted protection, administer Simparica Trio throughout the year without interruption.

The table below shows Simparica Trio packs with their dosage strengths.

Simparica Trio Dosing Table:

For Dogs:

Dogs should be tested for existing heartworms before beginning the treatment. Infected dogs should be treated to remove adult heartworms as per the vet's recommendation. The safety of Simparica Trio has not been evaluated in breeding, lactating and pregnant dogs. You should use Simparica Trio with caution in dogs with a history of seizures or other neurologic disorders. Do not use Simparica Trio in puppies and dogs under 8 weeks of age.

According to field studies, Simparica Trio was used together with anthelmintics, vaccines, antimicrobials, analgesics, antiprotozoals, anesthetic agents and NSAIDs without any side effects.

For Humans:

Simparica Trio is not for use in humans or any other animal species. You should keep these chews out of the reach of children, uninformed people and pets. In case of accidental ingestion, immediately consult a physician. Wash your hands after handling the treatment.

Are there Any Specific Storage Instructions for Simparica Trio?

Store Simparica Trio at or below 30°C (86°F).

What are the Key Benefits of Simparica Trio for Dogs?

• Unique trio formula: Combines three potent active ingredients, sarolaner, moxidectin, and pyrantel to deliver all-round coverage.
• Inside-out protection: Protects against both internal and external parasites.
• Tasty chew for easy administration: Delicious pork liver-flavored chew dogs readily accept, making dosing simple and easy.
• Broader tick coverage: One chew protects against six different tick species.
• Fast-acting: Known to begin killing fleas within hours of administration and continues to protect for the entire month.
• Puppy-safe: Safe for use in puppies as young as 8 weeks of age with at least 2.8 lbs of body weight.
• Allows flexible dosing: Can be given to dogs with or without food.

Is Simparica Trio safe for my puppy?

Simparica Trio is indicated for use in puppies and dogs as young as 8 weeks that weigh at least 2.8 lbs.

How frequently should I administer Simparica Trio?

You should administer one dose of Simparica Trio to your dog once every month.

How does Simparica Trio work?

Simparica Trio contains three active ingredients: sarolaner, moxidectin and pyrantel. After administration, the formula reaches the dog's bloodstream and is distributed to tissue fluids, just under the dog's skin. Sarolaner targets external parasites, including fleas and ticks. Moxidectin disrupts the neurotransmission of relevant parasites, protecting from heartworm disease. Pyrantel treats and controls intestinal worms, including roundworms and hookworms.

What if I miss a dose of Simparica Trio?

If you miss a dose, administer one immediately and continue with your dog's monthly dosing schedule.

How quickly does Simparica Trio work?

According to a lab study cited in the product label, Simparica Trio began killing fleas at four hours. The chews began killing black-legged ticks within eight hours.

How effective is Simparica Trio?

Lab studies referenced in the label suggest that one dose of Simparica Trio was 100% effective in preventing the development of heartworm disease when given as indicated. A lab study cited that the chews demonstrated complete flea efficacy at eight hours after administration and reduced the number of live ticks by more than 90% within 24 hours of infestation.

How is Simparica different from Simparica Trio?

Simparica contains one active ingredient, sarolaner. It protects dogs against fleas and different tick species. Simparica Trio contains three active ingredients: sarolaner, moxidectin and pyrantel. One dose of Simparica Trio protects dogs against fleas, ticks, heartworm disease, roundworms and hookworms. Both these treatments are indicated to prevent Lyme disease infections by killing black-legged vector ticks.

Is it safe to split Simparica Trio?

No, you should not split Simparica Trio chews.

Does Simparica Trio protect from Lyme disease?

Simparica Trio is indicated to prevent (Borrelia burgdorferi) infections that may cause Lyme disease by killing black-legged vector ticks.