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Revolution Plus for Cats

4.6/5 (272 Reviews)
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  • Information
  • Directions
  • Safety
  • Benefits
  • Revolution Plus FAQ
Information
Revolution Plus
  • Pet
    Cat
  • Treatment For
    Flea, Tick, Heartworm, Intestinal Worms
  • Health Benefits
    External & Internal Parasite Protection
  • Product Type
    Topical (liquid)
  • Parasites Covered
    fleas, Ticks, Heartworms, Roundworms, Hookworms, Ear Mites
  • Protects For
    One month
  • Recommended For
    8 weeks and older kittens, weighing 2.8 lbs or more
  • Key Ingredients
    Selamectin, Sarolaner

What is Revolution Plus for Cats?

Revolution Plus for Cats is a broad-spectrum treatment that safeguards your feline friend from both internal and external parasites. Carrying a legacy of over 25 years with Revolution (selamectin), it has been developed to provide more comprehensive protection. This all-in-one cat treatment comes in a small-volume, quick-drying and non-greasy topical solution for simple and easy administration.

A single dose of Revolution Plus topical every month ensures your cat is safe from fleas, heartworm disease, roundworms, hookworms, ear mites and flea tapeworms. Additionally, it kills four common types of ticks that can infect cats. Revolution Plus flea, tick & worm treatment features a unique dual-action (selamectin and sarolaner) composition, providing broader parasite protection. According to the manufacturer, it is the number one choice of veterinarians for cats.

Suitable For

Revolution Plus is suitable for kittens and cats from 8 weeks of age, weighing 2.8 lbs or greater.

Revolution Plus Indications

  • Prevents heartworm disease caused by Dirofilaria immitis.
  • Treats & controls roundworm (Toxocara cati) infections.
  • Treats & controls hookworm (Ancylostoma tubaeforme) infections.
  • Kills adult fleas.
  • Indicated for the treatment & prevention of flea infestations.
  • Indicated for the prevention of flea tapeworm (Dipylidium caninum) infections as a direct result of killing fleas that transmit tapeworm infections on a treated cat.
  • Treats and controls tick infestations (lone star tick, Gulf Coast tick, American dog tick & black-legged tick).
  • Treats and controls ear mite (Otodectes cynotis) infestations.

Ingredients: Selamectin, Sarolaner.

Directions
How to Use Revolution Plus for Cats

  • Measure your cat's weight to select the appropriate dosage.
  • Take a pipette out of the pack.
  • Puncture the seal of the pipette by firmly pressing its cap down. You will hear a clicking sound which confirms that the seal is broken.
  • Remove the cap to check whether the tip of the pipette is open.
  • Part the cat's hair on the back at the base of the neck between the shoulder blades until the skin is visible.
  • Place the tip of the pipette on your cat's skin.
  • Squeeze the pipette multiple times onto your cat's skin in one spot and empty the entire contents of the pipette.
  • Keeping the pipette squeezed, drag it away from the liquid and lift it to remove.
  • Make sure the pipette is empty.
  • After application, do not massage the liquid into the cat's skin.
  • For protection from heartworms, administer Revolution Plus monthly year-round or at least within one month after your cat's first exposure to mosquitoes and monthly afterwards until the end of the mosquito season.

The table below outlines the available Revolution Plus dosage packs based on your cat’s weight.

Revolution Plus Dosing Table:

Cat Size Cat Weight (lbs) Pack Color Pipette Volume (ml) Selamectin (mg/tube) Sarolaner (mg/tube) Doses Administered
Kittens & Small Cats 2.8 – 5.5 Yellow 0.25 15 2.5 One
Medium Cats 5.6 – 11.0 Orange 0.50 30 5.0 One
Large Cats 11.1 – 22.0 Green 1.00 60 10.0 One
For Cats over 22.0 lbs, administer the appropriate combination of Revolution Plus pipettes.
Safety

For Cats:

Do not use Revolution Plus in kittens under 8 weeks of age or less than 2.8 lbs of body weight. Use it with caution in cats with a history of seizures or neurologic disorders. The safe use of Revolution Plus has not been evaluated in breeding, pregnant or lactating cats. As per vet recommendation, cats 6 months of age or older may be tested for existing heartworm infections before beginning treatment with Revolution Plus.

Field studies suggest that Revolution Plus can be used with vaccines, antibacterials, cestocidal anthelmintics, sedatives, anesthetics, opioid analgesics, NSAIDs and corticosteroids.

For Humans:

Revolution Plus is not indicated for use in humans. Keep it out of the reach of children, pets and uninformed people. Do not allow children or anyone to come in contact with the application site until four hours after the application. Individuals with known hypersensitivity to any of the active ingredients should consult a physician before applying it to their cat.

General:

Revolution Plus is a flammable treatment. You should keep it away from heat, open flames, sparks or other sources of ignition.

Are there Any Specific Storage Instructions for Revolution Plus?

You should store this topical treatment at or below 30°C (86°F).

Benefits

What are the Key Benefits of Revolution Plus for Cats?

  • Trusted for over 25 years: Continues Revolution's legacy by providing extensive coverage.
  • Comprehensive protection: Safeguards cats against fleas, ticks, heartworm disease, roundworms, hookworms, ear mites and flea tapeworms.
  • Unique dual-action composition: Features two effective antiparasitics, selamectin and sarolaner, making it highly effective against parasites.
  • Multi-tick coverage: Kills four types of ticks for a full month.
  • User-friendly: Comes as a quick-drying, low-volume, and non-greasy topical solution for ease of application.
  • Safe & reliable: Suitable for use in kittens as young as 8 weeks of age.
Revolution Plus FAQ

What does Revolution Plus do for my cat?

When administered as indicated, Revolution Plus protects cats against fleas, ticks, heartworm disease, ear mites, flea tapeworms, roundworms and hookworms for one month.

How does Revolution Plus flea, tick & worm treatment work?

Revolution Plus contains active ingredients, selamectin and sarolaner. After application, the formula is absorbed into the cat's skin and bloodstream. Selamectin targets roundworms, hookworms and heartworms. Sarolaner eliminates fleas, ticks and ear mites.

How effective is Revolution Plus for cats?

According to a laboratory study referenced in the label, Revolution Plus began killing fleas within 12 hours of treatment and killed more than 90% of fleas within 24 hours. Another lab study cited in the label suggests its onset of tick-killing activity within 24 hours of administration.

It completely prevented the development of heartworms in cats infected with heartworm larvae (Dirofilaria immitis) 30 days before the treatment, according to lab studies referenced in the package insert.

Is Revolution Plus safe for my cat?

When used as directed, Revolution Plus is safe for use in kittens and cats 8 weeks of age and older, weighing 2.8 lbs or more. It is recommended that you consult a veterinarian before starting with any treatment.

How frequently should I use Revolution Plus on my cat?

Revolution Plus is a monthly broad-spectrum treatment. It is indicated for use once every month.

When should I bathe my cat after applying Revolution Plus?

For maximum efficacy of the treatment, you should bathe the animal first before applying the treatment. Let the cat's coat completely dry prior to dosing.

Can I use Revolution Plus with my cat's other treatments?

According to the product label, in field studies Revolution Plus was used alongside feline treatments, including vaccines, antibacterials, cestocidal anthelmintics, sedatives, anesthetics, opioid analgesics, NSAIDs and corticosteroids with no adverse reactions. However, you should consult with your vet before using it together with other treatments.

Can I use Revolution Plus on my cat with sensitive skin?

Revolution Plus is generally well-tolerated by cats, including those with sensitive skin. Talk to a veterinarian prior to using it on cats with sensitive skin.

Is it safe to use Revolution Plus on pregnant cats?

The safety of Revolution Plus has not been established in breeding, pregnant or lactating cats.

What is the difference between Revolution and Revolution Plus?

Revolution for cats contains selamectin as its active ingredient. It protects cats against fleas, heartworm disease, ear mites, roundworms and hookworms. Revolution Plus is composed of selamectin and sarolaner. It is effective in protecting cats from fleas, four tick species, heartworm disease, roundworms, hookworms and ear mites.

Do I need to test my cat for heartworms before using Revolution Plus?

After consulting a vet, cats 6 months of age or older may be tested for existing heartworm infections.

Can I use Revolution Plus year-round?

To provide your cats with continuous protection, you should use Revolution Plus year-round, regardless of the season.

Revolution Plus Reviews

4.6
Average Rating 4.6 Based on 272 Reviews
  • 5 star
     177
  • 4 star
     93
  • 3 star
     1
  • 2 star
     0
  • 1 star
     1
65%
Recommend
65% of Reviewers Recommend This Product
Write A Review
4.6/5
Average Rating 4.6
Based on 272 Reviews
Simple Cat Routine Aug 21, 2026
Quick application and easy to include in monthly care.
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Easy Cat Care Aug 14, 2026
Quick application and simple monthly routine.
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Ideal for Cats Aug 07, 2026
My cat stays flea-free and healthy. Application is quick and easy.
Was this review helpful? 0 1
Perfect Monthly Solution for Cats Jul 31, 2026
Perfect for my cat. No fleas, no worms, and super easy to apply monthly.
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Cat Comfort Jul 24, 2026
Keeps my cat protected and comfortable.
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Cat Protection Jul 10, 2026
Keeps my cat safe and itch-free.
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Cat Essential Jul 03, 2026
Keeps my cat safe and comfortable.
Was this review helpful? 1 0
Cat Friendly Jun 26, 2026
Works well for my cat’s protection needs.
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Broad Defense Jun 19, 2026
Works well for both internal and external parasites.
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All Round Care Jun 12, 2026
Works well for both internal and external pests.
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Broad Coverage May 29, 2026
Great for both fleas and internal parasites.
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